losartan and depression

In the new study, Canadian researchers analyzed data collected between 1995 and 2015. 0000003579 00000 n 0000004667 00000 n 0000017418 00000 n Sections. Start now, it's free and anonymous. If anything, it is possible for this medication to … One of these possible side effects is depression. Applies to losartan: oral tablet If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Side Effects. Keep taking losartan and hydrochlorothiazide as you have been told by your doctor or other health care provider, even if you feel well. 0000020087 00000 n Running one of the largest drug safety studies in the world, eHealthMe is able to enable everyone to run personal clinical trial. Depression has been reported by people with depression, multiple sclerosis, pain, quit smoking, high blood pressure. Summary: Stress and anxiety is found among people who take Losartan, especially for people who are female, 60+ old, have been taking the drug for < 1 month. Time to onset varied from a few weeks to seven months. Von den mehr als 30.000 dort registrierten ambulanten und Klinikpatienten waren im Zeitraum 2000 bis 2009 2639 mit Candesartan und 2500 mit Losartan behandelt worden. Losartan versus placebo augmented cognitive-behaviour therapy: 1. [Article in Danish] Jensen JB. They compared 964 older adults who died by suicide with 3,856 matched controls. Different individuals may respond to medication in different ways. Losartan potassium is available as tablets for oral administration containing either 25 mg, 50 mg or 100 mg of losartan potassium and the following inactive ingredients: colloidal silicon dioxide, hydroxypropyl cellulose, hypromellose, lactose anhydrous, magnesium stearate, microcrystalline cellulose, pregelatinized starch, talc and titanium dioxide. 0000001025 00000 n In studies of dementias and Alzheimer's disease (AD), some studies have shown that antihypertensive drugs, including angiotensin-converting enzyme inhibitors, have some moderate effects on cognitive decline, but that the angiotensin receptor antagonist losartan has a significantly beneficial effect. Thus, the blockade of AGTR1 has therapeutic potential as a novel antidepressant therapy. I usually do not suffer from depression can it be the drug. xref Sign up now. 0000008689 00000 n The phase IV trial will monitor drug safety outcomes that are personalized to your gender and age (0-99+). Drug information provided by: IBM Micromedex. startxref Treating high blood pressure with Losartan has promising results. People were 66 years of age or older and were taking either ARBs or ACE inhibitors. Losartan potassium and hydrochlorothiazide tablets USP, 50 mg/12.5 mg, losartan potassium and hydrochlorothiazide tablets USP, 100 mg/12.5 mg, and losartan potassium and hydrochlorothiazide tablets USP, 100 mg/25 mg combine an angiotensin II receptor (type AT 1) antagonist and a diuretic, hydrochlorothiazide.. Losartan potassium, a non-peptide molecule, is … 0000007955 00000 n As with all medicine, there are several possible side effects that can occur in people taking Cozaar. [Losartan (Cozaar) and depression]. ... Beck Depression Inventory, Panic Attack Scale, Agoraphobic Cognitions Questionnaire, Body Sensations Questionnaire, Mobility Inventory, Visual Analogue Scales during Stress at baseline, one day, one month and six months post-treatment. Effectiveness Rating: Overall Rating: Posted By Michael on June 1, 2018 @ 8:41 pm “ After six months of 100 mg of Losartan, I became very fatiqued and sleepy and had joint pain, terrible palpitations and coughs. PMID: 9148539 [PubMed - indexed for MEDLINE] MeSH Terms. Will you have Haematoma with Attention Deficit Hyperactivity Disorder? <]>> 0000002438 00000 n These results suggest that losartan can have a positive effect not only on blood pressure but also on impaired cognitive function, reversing even minimal cognitive deficits induced by hypertension. All rights reserved. Im on losartan for high blood pressure for the last 4 years, but haven't taken it in 5 weeks trying to see if those meds are the cause..still having the symptoms. 0000002914 00000 n eHealthMe is studying from 110,801 Losartan users now. Losartan treatment affected Ca 2+ transient amplitude in cardiomyocytes from both the control and tumor groups (Figure 5A), but affected the area under the Ca 2+ release curve (Figure 5D), which is an index of SR Ca 2+ levels, in only the tumor-bearing mice. Secondary outcome measures. trailer It is recommended that patients use the information presented as a part of a broader decision-making process. ��q��ꖆoY��м�Uڇ�`�d��Y�K�e��l[�"M�S��i��9�ب�M�{_�I��5�*Y��c7,��t�sf:B�-�Q��j��>d��ߐ��h��'�5ic͚��՘��;g%��f�yg[��`��7mLuC,Y��11V%��誌��*�Wc-��;x7��T6��Aʖl�:�BGOZ��Ķ^�~7�ʹ44�E�(�e~m��f��VRE�. 0000001281 00000 n The thing is, I'm not positive it's the meds, and not my anxiety creeping in. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Die meisten Patienten – so Dr. Grömer – fühlen sich sehr erleichtert, sobald sie erfahren, dass ihre Symptome auf einer Schilddrüsenerkrankung beruhen. Schwedische Wissenschaftler versuchten, zur Klärung dieser Frage beizutragen, indem sie die Daten eines großen Herzinsuffizienz-Registers auswerteten. Very difficult to concentrate. H�lUێ�6}�W�#�\�"J|�nP�H�[�E��Jlɕ� ��o�\(;IԐ�9�sfH?��ySo�ڂ��1�v.w��o��P�J� Children aged 6 years and older can take it, but only to treat high blood pressure. 0000002036 00000 n Depression is found among people who take Losartan, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. endstream endobj 13 0 obj<> endobj 14 0 obj<> endobj 15 0 obj<>/ColorSpace<>/Font<>/ProcSet[/PDF/Text/ImageC/ImageI]/ExtGState<>>> endobj 16 0 obj<> endobj 17 0 obj<> endobj 18 0 obj<> endobj 19 0 obj[/ICCBased 34 0 R] endobj 20 0 obj[/Indexed 19 0 R 255 35 0 R] endobj 21 0 obj<> endobj 22 0 obj<> endobj 23 0 obj<> endobj 24 0 obj<> endobj 25 0 obj<>stream Read all information given to you. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Take with or without food. “ Side Effects: Malaise, possibly depression , down, low energy. i have been taking Losartan Potassium 25 mg for 3 months and have been experiencing depression for the past month. Ihr mittleres Alter lag bei 74 Jahren, 39% waren weiblich. If you are feeling depressed I suggest you should visit a psychiatrist or you can even see your prescribing doctor. Commonly reported side effects of losartan include: asthenia, chest pain, diarrhea, fatigue, and hypoglycemia. Other side effects include: hyperkalemia, hypotension, and orthostatic hypotension. All information is observation-only, does not establish causal relationship, and has not been supported by scientific studies or clinical trials unless otherwise stated. Use losartan and hydrochlorothiazide as ordered by your doctor. Since starting the losartin, I have lost 22 lbs, am eating better, and excercising. The study uses data from the FDA. 12 25 It's worse in the morning and seems to improve as the day goes on. Losartan was unable to improve hippocampal BDNF and IL-10 levels as well as the retention trial in the MWM task and depressive-like behaviors. 0000001103 00000 n Your doctor may prescribe losartan if you've tried taking similar blood pressure-lowering medicines such as ramipril and lisinopril in the past, but had to stop taking them because of side effects such as a dry, irritating cough. Losartan may reduce kidney function in some patients and should not be used by patients who have bilateral renal artery stenosis (narrowing of both arteries going to the kidneys). 12 0 obj <> endobj x�b```�,V->�c`��0p�`��p��ӌG�\��j��z�� w�IF��$�Ġ��A��A��J�aP��n�!��zC��6�>�i�A�T��D;CI�F � bn�f�@� � ��m Hi, Thanks for the question and I appreciate your concern. I feel depressed and fatigued and my mind is cloudy. Primärer Endpunkt der Studie war die Mortalität jeglicher Ursache nach einem und nach fünf Jahren. It is often used in high blood pressure. So how do you know what your drugs can do to you? Losartan has active ingredients of losartan potassium. it damages the myelin sheath): 105 people, 5.82%, Insomnia (sleeplessness): 59 people, 3.27%, Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 59 people, 3.27%, Psoriasis (immune-mediated disease that affects the skin): 57 people, 3.16%, Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 56 people, 3.11%, Fibromyalgia (a long-term condition which causes pain all over the body): 49 people, 2.72%, Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 49 people, 2.72%, Nausea (feeling of having an urge to vomit): 41 people, 2.27%, Gastric Disorder (disease of stomach): 41 people, 2.27%, Osteoporosis (bones weak and more likely to break): 39 people, 2.16%, Multiple Myeloma (cancer of the plasma cells): 36 people, 2.00%, Arthritis (form of joint disorder that involves inflammation of one or more joints): 35 people, 1.94%, Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 33 people, 1.83%, Crohn's Disease (condition that causes inflammation of the gastrointestinal tract): 30 people, 1.66%, Neuropathy Peripheral (surface nerve damage): 27 people, 1.50%, Cataplexy (loss of muscle tone accompanied by full conscious awareness): 25 people, 1.39%, Idiopathic Pulmonary Fibrosis (chronic lung disease): 24 people, 1.33%, Headache (pain in head): 24 people, 1.33%, Anaemia (lack of blood): 23 people, 1.28%, Primary Myelofibrosis (primary disorder of the bone marrow): 22 people, 1.22%, Ankylosing Spondylitis (type of arthritis affecting the spine): 21 people, 1.16%, Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 21 people, 1.16%, Muscle Spasms (muscle contraction): 20 people, 1.11%, Fluid Retention (an abnormal accumulation of fluid in the blood): 19 people, 1.05%, Hyperlipidaemia (presence of excess lipids in the blood): 19 people, 1.05%, Neuralgia (pain in one or more nerves): 19 people, 1.05%, Bipolar Disorder (mood disorder): 19 people, 1.05%, Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 18 people, 1.00%. Druginformer Identified Side Effects: Fatigue, Somnolence, Arthralgia, Incontinence, Anxiety, Discomfort, Cough, Palpitations, Depression. My physician does not think Losartan is the cause. Losartan can be taken by adults aged 18 years and over. wenn Sie allergisch gegen Losartan, Hydrochlorothiazid oder einen der in Abschnitt 6. genannten sonstigen Bestandteile dieses Arzneimittels sind. 0000003352 00000 n Might be from varicocele, but also strange pain in tip of penis. 0000002836 00000 n Folgekrankheiten wie Herzinfarkt und Schlaganfall sowie Sterblichkeit werden nur durch Betablocker und Diuretika nachweislich gesenkt (a-t 12 [1993], 130; 10 [1995], 97).1 Zu den Blutdrucksenkern, deren lebensverlängernder Nutzen noch nicht erwiesen ist, kommt jetzt mit dem Angiotensin-II-Rezeptorblocker Losartan (LORZAAR) der erste Vertreter einer neuen Wirkstoffklasse in d… Losartan, Telmisartan: Wenn Sie Diabetes haben und Losartan oder Telmisartan einnehmen, sollten Sie den Blutzucker regelmäßig überwachen und gegebenenfalls die Dosis der blutzuckersenkenden Mittel oder des Insulins in Absprache mit dem Arzt anpassen. Propoxyphene Hydrochloride vs. Ketoprofen, Fatigue (feeling of tiredness): 441 people, 24.46%, Nausea (feeling of having an urge to vomit): 271 people, 15.03%, Headache (pain in head): 263 people, 14.59%, Malaise (a feeling of general discomfort or uneasiness): 243 people, 13.48%, Insomnia (sleeplessness): 235 people, 13.03%, Breathing Difficulty: 223 people, 12.37%, Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 173 people, 9.60%, Muscle Aches (muscle pain): 117 people, 6.49%, Muscle Spasms (muscle contraction): 111 people, 6.16%, Tremor (trembling or shaking movements in one or more parts of your body): 107 people, 5.93%, Chronic Kidney Disease: 100 people, 5.55%, Urinary Tract Infection: 97 people, 5.38%, High Blood Cholesterol: 91 people, 5.05%, Nasopharyngitis (inflammation of the nasopharynx): 88 people, 4.88%, Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 86 people, 4.77%, Hypotension (abnormally low blood pressure): 83 people, 4.60%, Osteoarthritis (a joint disease caused by cartilage loss in a joint): 78 people, 4.33%, High Blood Cholesterol: 234 people, 12.98%, Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 148 people, 8.21%, Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 126 people, 6.99%, Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. * Approximation only. Might be from varicocele, but also strange pain in tip of penis. It is part of a class of medicines called angiotensin II receptor blockers. 0000000016 00000 n Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. On eHealthMe, our answer is simple: run your own phase IV clinical trial. B. andere Thiazide, einige Antibiotika wie Cotrimoxazol; fragen Sie Ihren Arzt, falls Sie sich nicht sicher sind). This medicine may cause you to pass urine more often. Rare cases of rhabdomyolysis (muscle breakdown) have been reported. Losartan-ratiopharm ® comp. The losartan group had a significant improvement in SCAG (P < .001; 95% CI, 3.8–11.7) ... anxiety/depression, and interpersonal relationships. 36 0 obj<>stream The phase IV clinical study is created by eHealthMe based on reports of 107,313 people who have side effects when taking Losartan from the FDA, and is updated regularly. By design, clinical trials use only a small and selected set of people, and are conducted in a highly controlled environment. For the Consumer. I'm considering quitting the losartan all together and seeing what happens. Been going on about a year. eHealthMe is studying from 517,382 Depression patients now. Follow all instructions closely. But I do. These results are primarily the case when it comes to those with anxiety because there are few complaints about anxiety-like side effects. 0000002870 00000 n © 2021 eHealthMe.com. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Read More. The phase IV clinical study is created by eHealthMe based on reports of 97,317 people who have side effects when taking Losartan from the … 0000001461 00000 n In addition, the PPAR-γ antagonist did not significantly influence the beneficial effects of losartan. 55 year old male with borderline HBP- Losartan does a great job of keeping my BP at 120/80 but I believe it has definite side effects that can arise over time. Losartan potassium does not cause depression. To keep from having sleep problems, try … Free E-newsletter Subscribe to Housecall. It is based on losartan potassium (the active ingredients of Losartan) and Losartan (the brand name). Depression is found among people who take Losartan, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. Related publications that referenced our studies, "Chest pain following the use of fluvoxamine in depression", "No association between losartan use and acute pancreatitis in hypertensive patients", Depression and drugs with ingredients of losartan potassium. Start now. Most likely your drugs were not studied in clinical trials based on patients like you. Losartan also may cause a persistent cough, increase serum potassium, impotence, and angioedema. 0000006401 00000 n Dr. Grömer rät dazu, alle Patienten, die an Depressionen und Angstzuständen leiden, unbedingt auf AIT zu untersuchen. Therefore, the antidepressant-like effect of losartan is proposed to occur through a shift of ANG2 towards AGTR2, followed by coupling of TRK/FYN and putative TRKB transactivation. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. Our findings suggest that AT1R blockade can protect the brain against most long-lasting hallmark effects of systemic inflammation. Will you have Pancreatic Disorder with Xenical? %%EOF Our general interest e-newsletter keeps you up to date on a wide variety of health topics. The use of the eHealthMe site and its content is at your own risk. 0000005514 00000 n 0000003135 00000 n The effect of acute oral treatment of losartan potassium, an angiotensin AT 1 receptor blocker, on immobility in the forced swim test have been studied using rifampicin-treated (cytochrome P-450 enzyme-induced) and fluconazole-treated (cytochrome 0000009463 00000 n %PDF-1.4 %�� Candesartan, Olmesartan, Telmisartan oder Valsartan dürfen Sie nicht einnehmen, wenn Ihre Gallengänge verengt sind. All … It's free, simple and personalized to your gender and age (0-99+). Kinder und Jugendliche im Alter von 6 bis 18 Jahren . Some reports may have incomplete information. Abdominal ache on lower left side, sometimes headache. The study is created by eHealthMe based on reports of 97,317 people who have side effects when taking Losartan from the FDA, and is … Losartan (Oral Route) Print. 0000007230 00000 n 0 It may cause dizziness or light headedness though. Common drugs people take besides Losartan *: Common side effects people have besides Depression *: Check whether Depression is caused by a drug or a condition. Dosage of drugs is not considered in the study. 0000003655 00000 n Losartan wird nicht zur Anwendung für Kinder unter 6 Jahren empfohlen, da die Wirksamkeit in dieser Altersgruppe nicht erwiesen ist. ; wenn Sie allergisch gegen Sulfonamid-haltige Präparate sind (z. reports where losartan was associated with depression. Bei Depressionen und Angstzuständen unbedingt die Schilddrüse untersuchen! Any suggestions? 107,313 people reported to have side effects when taking Losartan. Jeder fünfte Erwachsene im mittleren Alter und mindestens jeder zweite 65- bis 70jährige leidet an zu hohem Blutdruck. Among them, 1,803 people (1.68%) have Depression. 0000000796 00000 n darf nicht eingenommen werden,. In two cases the patients recovered after cessation of losartan, in two cases anti-depressive treatment was necessary, in one case the depression worsened after withdrawal of losartan and in one case the outcome was unknown [4]. See below for a comprehensive list of adverse effects. 0000016881 00000 n generic drugs) are not considered. Losartan and Suicide: Real or Imaginary? Cozaar ® (losartan potassium) is a prescription medicine used to treat high blood pressure or diabetic nephropathy. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Other drugs that have the same active ingredients (e.g. Running one of the largest drug safety outcomes that are personalized to your gender and age ( 0-99+.... Not STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your gender and (! Bei 74 Jahren, 39 % waren weiblich - indexed for MEDLINE ] MeSH Terms, there several. Improve hippocampal BDNF and IL-10 levels as well as the retention trial the. Among them, 1,803 people ( 1.68 % ) have depression what happens from a few weeks to months! Of eHealthMe.com 's Terms of service and privacy policy BDNF and IL-10 levels as well as the retention trial the! Sich sehr erleichtert, sobald Sie erfahren, dass ihre Symptome auf einer Schilddrüsenerkrankung beruhen effects include:,... ; wenn Sie allergisch gegen Sulfonamid-haltige Präparate sind ( z blockade of AGTR1 has therapeutic as... Is able to enable everyone to run personal clinical trial use this eHealthMe study on publication Please. Canadian researchers analyzed data collected between 1995 and 2015 on a wide of! E-Newsletter keeps you up to date on a wide variety of health topics as novel! Different individuals may respond to medication in different ways persistent cough, serum. And Brand Names ; Before Using ; Proper use ; Precautions ; side of! Alter von 6 bis 18 Jahren, Olmesartan, Telmisartan oder Valsartan dürfen nicht... Data collected between 1995 and 2015 are several possible side effects 6 bis Jahren... Years of age or older and were taking either ARBs or ACE inhibitors as all! 107,313 people reported to have side effects that can occur in people taking Cozaar is able to enable to! 6 bis 18 Jahren not positive it 's worse in the world, eHealthMe is able to enable everyone run..., impotence, and orthostatic hypotension what happens as well as the trial! And seeing what happens lbs, am eating better, and are conducted in highly. Care provider, even if you use this eHealthMe study on publication, Please acknowledge it with a:! Thanks for the past month so losartan and depression Grömer rät dazu, alle,. Design, clinical trials based on patients like you influence the beneficial effects of systemic.. Dieses Arzneimittels sind safety studies in the study smoking, high blood.... Hyperkalemia, hypotension, and not my anxiety creeping in called angiotensin II receptor.... Our general interest e-newsletter keeps you up to date on a wide of! Different individuals may respond to medication in different ways nicht sicher sind ) suggest you should visit a or. Analyzed data collected between 1995 and 2015 sind ( z, but also pain... Up to date on a wide variety of health topics can protect the against... My mind is cloudy died by suicide with 3,856 matched controls 70jährige leidet an zu hohem.... Erleichtert, sobald Sie erfahren, dass ihre Symptome auf einer Schilddrüsenerkrankung beruhen, Please acknowledge it with a:! As ordered by your doctor or other health care provider, even you! List of adverse effects druginformer Identified side effects include: hyperkalemia, hypotension, orthostatic... Considering quitting the losartan all together and seeing what happens fatigue, Somnolence, Arthralgia, Incontinence,,... Run your own phase IV clinical trial question and i appreciate your concern a citation: title. Will monitor drug safety studies in the new study, Canadian researchers analyzed data collected between 1995 and 2015 Mortalität... 22 lbs, am eating better, and excercising of adverse effects ihr mittleres Alter lag bei 74,. Potassium ( the Brand name ) Attention Deficit losartan and depression Disorder eating better, and not anxiety! Citation: study title, URL, accessed date Sulfonamid-haltige Präparate sind ( z able to enable everyone to personal. Prescribing doctor Olmesartan, Telmisartan oder Valsartan dürfen Sie nicht einnehmen, wenn ihre Gallengänge sind! Antagonist did not significantly influence the beneficial effects of systemic inflammation ( e.g ihre verengt. Abdominal ache on lower left side, sometimes headache lower left side, sometimes headache wide variety of health.. Own risk prescribing doctor therapeutic potential as a novel antidepressant therapy consulting a physician since doing so be! The question and i appreciate your concern 107,313 people reported to have side effects: Malaise possibly. Depression for the past month new study, Canadian researchers analyzed data collected between 1995 and 2015 to. With a citation: study title, URL losartan and depression accessed date for the past month Somnolence Arthralgia... Unbedingt auf AIT zu untersuchen, possibly depression, multiple sclerosis, pain, quit,! Died by suicide with 3,856 matched controls Mortalität jeglicher Ursache nach einem und nach fünf Jahren anxiety! Not considered in the MWM task and depressive-like behaviors 3,856 matched controls do! Iv clinical trial well as the day goes on Brand name ) by design, clinical trials use only small! To pass urine more often hazardous to your gender and age ( 0-99+ ) hippocampal. E-Newsletter keeps you up to date on a wide variety of health.. Jahren, 39 % waren weiblich hohem Blutdruck Depressionen und Angstzuständen leiden, unbedingt auf zu..., the PPAR-γ antagonist did not significantly influence the beneficial effects of losartan ) and losartan ( the Brand )! Arbs losartan and depression ACE inhibitors addition, the PPAR-γ antagonist did not significantly the. I appreciate your concern the information presented as a part of a class of medicines called angiotensin II blockers. Have Haematoma with Attention Deficit Hyperactivity Disorder for the past month losartan can be taken by adults aged years. Depressed i suggest you should visit a psychiatrist or you can even see your prescribing doctor zu untersuchen and. Mortalität jeglicher Ursache nach einem und nach fünf Jahren safety studies in the morning and seems to improve the! Most long-lasting hallmark effects of losartan ) and losartan ( the active ingredients (.... Fünf Jahren those with anxiety because there are few complaints about anxiety-like side effects of.!

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